Bursa-Vac® 3

BURSA-VAC® 3 is a live virus vaccine of chicken embryo origin containing an intermediate classic strain of infectious bursal disease. It is a broadspectrum vaccine with the ability to induce protection against IBD challenge in broilers and commercial layers, and maximum response to inactivated IBD vaccines in breeders.

Composition
chicken embryo origin containing an intermediate classic strain of infectious bursal virus.

Formulation
A freeze-dried pellet.

Indications
Immunization of chickens against Gumboro Disease (IBD).

When to Vaccinate
Vaccinate by spray cabinet application or subcutaneously at day of age or by drinking water at 2 weeks of age or older. Good management practices should be followed to reduce exposure of birds to infectious bursal disease virus during the first several weeks of life.

Your Vaccination Program
The development of a durable, strong protection depends upon the use of an effective vaccination program as well as many circumstances such as administration techniques, environment and flock health at time of vaccination. Also, the immune response to one vaccination under field conditions is seldom complete for all animals within a given flock. Even when vaccination is successful, the protection stimulated in individual animals against different diseases may not be life long. Therefore, under certain circumstances revaccination may be necessary.

Preparation of the Vaccine
FOR INTRAOCULAR USE

  1. Do not open and mix the vaccine until ready to begin vaccination. Use vaccine immediately after mixing.
  2. Tear off the aluminum seal from the vial containing the dried vaccine.
  3. Lift off the rubber stopper.
  4. Remove the aluminum seal and rubber stopper from the polyethylene bottle of diluent.
  5. Carefully pour diluent into the vaccine vial until it is approximately two-thirds full.
  6. Replace the rubber stopper and shake.
  7. Pour the partly dissolved vaccine into the bottle containing the rest of the diluent.
  8. Replace the rubber stopper and shake vigorously until all material is dissolved. (Use applicator insert for Intraocular Administration.)

FOR SPRAY CABINET USE

  1. Do not open and mix vaccine until ready for use.
  2. Only mix enough vaccine to last one hour at a time.
  3. Remove the tear-off aluminum seal from the vaccine vial without disturbing the rubber stopper.
  4. Use 70 ml of cool, non-chlorinated tap water to dilute each 1,000 doses of vaccine.
  5. Submerge the vial in the appropriate volume of non-chlorinated tap water and lift the lip of the stopper to allow water to enter the vial.
  6. Reseat the stopper and shake thoroughly to dissolve the vaccine.
  7. Pour the dissolved vaccine into the spray apparatus reservoir.
  8. Rinse the vial twice with non-chlorinated tap water to remove any residual vaccine from the vial.

FOR WATER USE

  1. Do not open and mix vaccine until ready for use.
  2. Remove the tear-off aluminum seal from the vaccine vial without disturbing the rubber stopper.
  3. Use cool, clean, non-chlorinated tap water to which powdered milk has been added as directed under How to Vaccinate.
  4. Holding the vial submerged in a pail of water or under a running stream of water, lift the lip of the rubber stopper so that the water (milk added) is sucked into the vial.
  5. Reseat the stopper and shake to thoroughly dissolve the vaccine.

How to Vaccinate
INTRAOCULAR METHOD
For chickens 4 weeks of age or older.

  1. Place one full drop of vaccine into the open eye.
  2. Do not release the chicken until after it has swallowed.

SPRAY CABINET METHOD

  1. Proper spray cabinet application of this vaccine is accomplished only through the use of a clean, disinfectant-free spray cabinet. The spray cabinet should be adjusted to deliver 7 ml per 100- bird chick box. The cabinet should be operated at a pressure of 35-42 lbs.
  2. Using appropriate clean, sterile, disinfectant-free tubing, hook up the final mixed vaccine to the spray cabinet. Make sure all air bubbles are removed from the delivery tubing and that the proper dosage is delivered consistently with each tripper-spray.
  3. Place a chick box containing 100 chicks in the spray cabinet and trigger the sprayer one time to administer one dose per chick.

DRINKING WATER METHOD
Do not mix the vaccine into the drinking water until ready for use.
Drinking water for vaccination should be mixed with powdered milk to prevent inactivation from chlorine or other water additives and also to stabilize the vaccine virus. The powdered milk should be added to the water at the rate of 3 grams per 11 liters (one heaped teaspoon per 3 U.S. gallons or 2.5 Imp. Gallons); or 90 grams per 300 liters (one heaped cupful per 80 U.S. gallons or 66 Imp. Gallons).
Withhold water for several hours before vaccinating so birds are thirsty. Thoroughly clean and rinse all watering containers so that no residual disinfectants remain. Dilute the vaccine immediately before use with cool, clean, non-chlorinated water (milk added). Pour the dissolved vaccine material into water and mix thoroughly.
Distribute diluted vaccine so that all birds are able to drink within a 1 hour period and do not add any more water until the vaccine is consumed. Avoid placing water in direct sunlight.

Caution

  1. For Veterinary Use Only.
  2. For spray cabinet application, use only in day old chicks. For use by drinking water in chickens 2 weeks or older.
  3. All chickens within a house should be vaccinated on the same day. Isolate other susceptible chickens on the premises from chickens being vaccinated.
  4. Vaccinate only healthy chickens. Although disease may not be evident, coccidiosis, chronic respiratory disease, mycoplasma infection, lymphoid leukosis, Marek’s disease, or other disease conditions may cause serous complications or reduce protection.
  5. In outbreak situations, vaccinate healthy chickens first, progressing toward outbreak areas in order to vaccinate diseased chickens last. Do not spill or spatter the vaccine. Use entire contents of vial when first opened.
  6. Burn empty bottles, caps and all unused vaccine and accessories.
  7. Wash hands thoroughly after using the vaccine.
  8. Do not dilute the vaccine or otherwise stretch the dosage.
  9. Store at 7°C (45°F).
  10. Do not vaccinate within 21 days before slaughter.
  11. Care should be taken to avoid the spread of virus from vaccinated flocks to clean premises.
  12. Use only in states where permitted and on premises with a history of bursal disease.

Records
Keep a record of vaccine type, quantity, serial number and expiration date; the date and time of vaccination; the number, age, breed, and location of the chickens; names of operators performing the vaccination and any observed reactions.